Single women sex no register
No patients were involved in setting the research question or the outcome measures, nor were they involved in developing plans for design or implementation of the study.No patients were asked to advise on interpretation or writing up of results.
In the EFEMERIS database, information on hospital admission during pregnancy was not available so women admitted with influenza were not excluded in the French data.
There are no plans to disseminate the results of the research to study participants or the relevant patient community.
We defined exposure as having filled a prescription after the date of assumed conception (that is, from 14 days after the first day of the last menstrual period), for either of the two neuraminidase inhibitors—oseltamivir (ATC code J05AH02) or zanamivir (ATC code JO5AH01)—as recorded in the prescribed drug registers or the EFEMERIS database.
No randomised controlled trials on use of neuraminidase inhibitors during pregnancy have been conducted.
To date, seven observational studies including data from a total of approximately 2500 women who used oseltamivir during pregnancy found no increased risks of congenital malformations or other adverse pregnancy outcomes.591011121314 The largest study so far was from Canada and included around 1200 exposed women.Only singleton infants born at 154 days (22 weeks) of gestation or later were included.